IUI or IVF. Comparison Intrauterine Insemination and In Vitro Fertilization
For many, such an approach becomes unexpected, as well as a difficult decision to make. How does intrauterine insemination (IUI) happen, its stages, effectiveness, indications and the chances for a result is described in this article. In short, the method comprises of administering the selected and capacitated sperm into the uterus. Nowadays to do this the sperm of the husband or a donor sample is used. The technique is as similar to natural conception as it is possible. But the impact is higher. If during natural intercourse pregnancy occurs in 6-7% in one cycle, during the IUI you can expect to result in 10-15% of the attempts.
IUI or IVF?
In IVF the results are clearly better, they reach 40 per cent or more. Plus, there are additional methods that increase the odds - they are PICSI, ICSI, IMSI, PGD, assisted hatching and others. Each of them has its own advantages and disadvantages. They are used at individual indications. But the cost of IVF, medicamental and psychological stress on the body is much higher. The following information will help you make the choice between intrauterine insemination or IVF.
Advantages of Insemination before IVF:
- There is no risk to the woman's body.
- No need to hold a powerful hormonal stimulation. Although at the indications the stimulation may still be used, but a gentler one.
- The relatively low cost of the procedure.
What is the difference between IUI and IVF?
To fully understand the advantages of intrauterine insemination compared with IVF, it is necessary to understand what is the difference.
Table. What is the difference between IUI and IVF?
Intrauterine insemination by the sperm of the husband
Intrauterine insemination with the sperm of the husband - a method used to treat infertility, it has a maximum similarity with natural conception and a minimal interference in the process of fertilization.
Resorted to when:
- subfebril sperm - Lowered qualitative and quantitative indicators;
- retrograde ejaculation;
- ejaculatory-sexual disorders;
- a small amount of ejaculate;
- high viscosity of the seminal plasma (liquid);
- the presence of sperm antibodies;
- state of health after chemotherapy and vasectomy (surgery to efferent seminal ducts, after which the man with a preserved sexual function cannot conceive a child independently);
- the use of frozen semen;
- 4 or more unsuccessful attempts to intracervical insemination (injection of male gametes into the cervical canal).
From the woman's indications as follows:
- infertility of unknown etiology (origin);
- various diseases and disorders in the structure of the cervix - called cervical factor;
- the presence of sperm antibodies;
- vaginismus - the impossibility of vaginal penetration;
- allergic reactions to sperm of her husband;
- ovulatory dysfunction that is treatable.
The failure of intrauterine insemination with the husband’s sperm brings up the need for the doctor, and, consequently, the married couple to use more sophisticated techniques of assisted reproductive medicine.
Intrauterine insemination by donor biological material
After repeated attempts of low performance during intrauterine insemination with the sperm of the husband, in some cases, the doctors, before moving on to in vitro fertilization, recommend IUI with the use of donor sperm. This can be caused by different reasons. The doctor takes into account the state of health, the age of the woman, the previous attempts at insemination and may deem inexpedient to go for IVF until more simple and accessible methods have been tried. But to use a sperm donor coordination in the relations between the couple is required as well as their mutual consent. Without the consent of the husband intrauterine insemination cannot be carried out. The donor may be a relative or an acquIUIntance. If a couple does not have such possibility, frozen donor sperm from the cryobank may be used. In this case, the donor is an anonymous person.