Advantages of PGD
PGD - preimplantation genetic diagnosis. It is carried out in order to identify viable embryos without genetic abnormalities. Advantages of PGD for families with infertility - increases the chance of a successful pregnancy.
How is PGD done?
Analysis of chromosomal abnormalities of embryos is held on 46 chromosomes, ie the full chromosome set of the cells. This way, any number of disorders of chromosomes is excluded, rather than a limited list. This information is most important for the prevention of miscarriage in early pregnancy.
What does doing PGD give to families with infertility?
Finding and excluding the defective embryos allows for a 30% increase for the success of IVF, reduces the risk of spontaneous abortion, minimizes the number of unsuccessful attempts of transfer. Overall, this reduces the cost of IVF, because pregnancy faster and eliminates the need for long-term use of hormonal drugs, which has a positive effect on women's health.
In terms of genetics, it significantly reduces the risk of having a child with chromosomal disorders (eg, Down syndrome). In addition, PGD allows simultaneous diagnosis of monogenic hereditary diseases and chromosomal abnormalities.
What does holding PGD give to families with a hereditary disease?
PGD allows you to check multiple embryos. Those that will not be used at the first attempt, can be cryopreserved for future use, which reduces the burden on the woman's body. Since the diagnosis is done in the early stages of the embryo division, there is no need for an early termination of pregnancy in the case, if you find a chromosomal abnormality.
This way you get a choice - because with IVF usually come a few embryos, among them almost always it is possible to find an embryo, which hasn’t inherited the familial disease.
If you are not confident in your genetic safety, or you want to eliminate the risk of conceiving a child with genetic abnormalities, PGD allows you to avoid doubts and anxieties related to the future of your baby.
Head of the Department of Clinical Genetics, a physician-geneticist